Hydrocodone 10/660mg
Hydrocodone 10/660mg Price range: 294,00€ through 654,00€
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Hydrocodone 10/500mg
Hydrocodone 10/500mg Price range: 292,00€ through 652,00€

Hydrocodone 10/650mg

Price range: 293,00€ through 653,00€

* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

⚠️ Critical Safety Alert

  • NOT AVAILABLE in U.S. since 2014 – All opioid/APAP combos now limited to ≤325mg APAP per unit

  • Extreme Hepatotoxicity Risk:

    • Just 6 tablets = 3,900mg APAP (exceeds daily max)

    • 8 tablets = 5,200mg (acute liver failure range)


If Encountering This Product:

  1. DO NOT ADMINISTER – Likely counterfeit/foreign

  2. REPORT to FDA MedWatch

  3. SWITCH IMMEDIATELY to safer alternatives


Current FDA-Approved Alternatives

Product Hydrocodone APAP Status
Norco 5/7.5/10mg 325mg Available
Hysingla ER 10-120mg 0mg No APAP risk
Zamicet 10mg 300mg Rare specialty product

Why 650mg APAP Was Banned:

  • #1 Cause of Acute Liver Failure in U.S. (2000s)

  • Fatal Overdoses from unintentional APAP stacking

  • No Therapeutic Benefit over 325mg formulations


Proper 10mg Hydrocodone Dosing Today

  1. Standard 10/325mg:

    • Max 6 tabs/day (1,950mg APAP)

  2. APAP-Free Options:

    • Hysingla ER (pure hydrocodone)

    • Combine hydrocodone IR with separate APAP


Patient Counseling Points

✔ Never combine with other APAP products
✔ Watch for hidden APAP in cold/flu meds
✔ Early OD signs: Nausea, RUQ pain, confusion


Need legitimate pain management?
Consult a physician for:

  • Non-APAP opioids

  • Multimodal therapies

  • Personalized risk assessment

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