Valium® (Diazepam) 10mg – The Gold-Standard Benzodiazepine for Acute Symptom Control
Trusted anxiolytic, muscle relaxant, and anticonvulsant with decades of clinical validation
Premium Therapeutic Benefits
✔ Rapid Anxiety Relief – Noticeable calm within 30 minutes
✔ Extended Duration – Active metabolites provide prolonged effects (up to 48 hours)
✔ Versatile Administration – Oral, IV, IM, or rectal (for seizures)
✔ Muscle Relaxation – Direct action on spinal cord reflexes
Optimal Clinical Uses
• Acute panic attacks (short-term crisis management)
• Muscle spasm relief – Especially back injuries/spinal conditions
• Alcohol withdrawal protocol (CIWA-Ar guideline recommended)
• Pre-procedure sedation (dentistry/endoscopy)
• Seizure emergencies (when IV access unavailable)
Precision Dosing Guide
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Standard Adults: 2-10mg 2-4x daily (max 30mg/day)
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Elderly/Debilitated: 2-5mg 1-2x daily
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Status Epilepticus: 5-10mg IV every 10-15min PRN
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Half-Life: 20-100 hours (including active metabolites)
Exclusive Advantages
→ Proven reliability since 1963 (original benzodiazepine)
→ Smooth taper profile due to long-acting metabolites
→ Flexible formulations – Tablets, injection, rectal gel
→ Cost-effective – Multiple generic options available
Safety-First Features
⚠️ DEA Schedule IV – Requires vigilant prescribing
⚠️ Boxed Warning:
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Risk of fatal respiratory depression with opioids
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Potential for dependence/addiction
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Neonatal withdrawal syndrome
Patient-Specific Considerations
• Best for: Short-term use (<2-4 weeks)
• Avoid in: Severe hepatic impairment, untreated OSA
• Critical Interaction: Opioids, alcohol, CYP3A4 inhibitors
• Discontinuation: Must taper to prevent withdrawal
Identification & Packaging
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Brand Tablets: Blue, scored, “VALIUM 10” imprint
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Generics: Multiple manufacturers (same bioequivalence)
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Hospital Formulations:
• 5mg/mL injectable vials
• Diastat® rectal delivery system
