Percocet 10/325mg

Percocet 10/325mg – Dual-Action Pain Relief for Moderate to Severe Acute Pain

Combination opioid/acetaminophen formula for effective short-term pain management

Key Features:
✔️ Powerful Analgesic – 10mg oxycodone (Schedule II opioid)
✔️ Enhanced Effect – 325mg acetaminophen boosts pain relief
✔️ Immediate Release – Fast-acting for acute pain episodes
✔️ 4-6 Hour Duration – Balanced therapeutic window

Clinical Indications:
• Post-surgical pain
• Major injury recovery
• Severe dental procedures
• Trauma-related pain
• Cancer pain (as part of regimen)

Dosing Protocol:

• Adults: 1 tablet every 4-6 hours as needed for pain

• Max Daily Limit: 6 tablets/24hr (≤4g acetaminophen)

• Short-Term Use Only – Typically ≤5 days for acute pain

• Take with Food – Minimizes GI discomfort

Safety Warnings (Black Box):
⚠️ HIGH ADDICTION POTENTIAL – Strictly follow prescribing instructions
⚠️ Respiratory Depression Risk – Especially with other CNS depressants
⚠️ Acetaminophen Toxicity – Do not exceed 3250mg/day (chronic use)
⚠️ NEVER Crush/Chew – Avoid rapid release/abuse potential

Patient Considerations:
→ Requires opioid-naive patients to start with lower doses (2.5/325 or 5/325)
→ Not for chronic pain management without special protocols
→ Must store securely to prevent misuse/theft
→ Always use with non-opioid adjuvants when possible

Monitoring Requirements:
• Regular physician follow-ups
• Pain diary documentation
• Bowel regimen for constipation
• Respiratory rate checks

Discontinuation Protocol:

• Taper gradually to prevent withdrawal

• Never stop abruptly after prolonged use

• Watch for rebound pain

Available Formats:

• Round white tablets (imprint varies by manufacturer)

• 100-count bottles with safety cap

• Blister packs for controlled dispensing

Prescription Limitations:
▸ Requires written prescription (no refills) in most states
▸ Mandatory PDMP checks before dispensing
▸ Often requires pain management contract

This medication should only be used under strict medical supervision as part of a comprehensive pain management plan.