Viagra 150mg

Viagra® (Sildenafil Citrate) 150mg – High-Potency ED Therapy
(Non-Standard Dose – Specialized Use Only)

⚠️ Critical Safety Advisory

• Exceeds FDA-Approved Maximum (100mg/day)

• Requires Urologist Supervision

• Not Commercially Manufactured

Theoretical Application

✔ Treatment-Resistant ED (After failed 100mg trials)
✔ Severe Vascular Insufficiency (Case-by-case basis)
✔ Short-Duration, High-Intensity Therapy

Heightened Risk Profile

🛑 Cardiovascular:

• Acute hypotension with nitrates

• Myocardial ischemia risk during activity

🛑 Prolonged Erections:

• 4.7x higher priapism risk vs 50mg

🛑 Neurological:

• Severe headaches (23% incidence)

• Blue-tinted vision (dose-dependent)

Pharmacokinetics

• Onset: 30-45 minutes (fasting)

• Duration: 8-10 hour window

• Metabolism: Hepatic (CYP3A4)

Mandatory Safety Protocols

✅ Cardiac Clearance Required (Stress test if >40yo)
✅ Priapism Emergency Plan (Ice packs, ER contacts)
✅ Absolute Contraindications:

• Nitrate therapy

• Recent stroke/MI

• Retinitis pigmentosa

Clinically Preferred Alternatives

Off-Label Use Requirements

1. Documented failure of 100mg dose

2. Signed informed consent

3. Baseline ECG and BP monitoring

4. Initial supervised trial dose